A full biological image consists of the sum of its individually analysed elements. In order to put all the puzzle pieces together, Merck has developed the largest base of immunoassays for soluble intercellular and biomarkers, including a complete range of Luminex® instruments.
Biomarkers and immunodiagnostic tests
Merck offers many multiplex and single protein analyses for intracellular and soluble biomarkers. Multiplex instruments adapted to perform the necessary multiplex analysis will give you freedom to maximize the use of Luminex® xMAP® technology for biomarker testing and protein analysis. Luminex® multiplex instruments are used when it comes to high-density and high performance at the same time.
Western blotting and IHC
The Western blotting approach is one of the techniques most commonly used in laboratories, especially if you still have difficulties in obtaining consistent and quality results. Merck offers a variety of products, including optimized Western blotting reagents for fluorescence and chemiluminescence, as well as the SNAP i.d.® 2.0 system that decreases the blocking and antibody incubation time from hours to minutes.
The Direct Detect® spectrometer is the first infrared (IR) biomolecular assay system. For more accurate results, the absorption of proteins and peptide amide groups is measured with IR spectrometry. Compared to conventional colorimetric analysis, this method is more accurate and faster. It is recommended for use with detergents, reducing compounds and other buffer components that prevent sample analysis by traditional protein determination methods. Analysis requires only 2 μL of the sample, which is especially important when using expensive samples. Thanks to a new software module, it is now possible to analyze the long aliphatic chains of lipids and detergents.
Antibodies and analysis
Merck pays special attention to antibodies and research. Along with Upstate® and Chemicon®, Merck supplies validated antibodies to the market for the following areas of research: neuroscience, epigenetics, cell signalling, cancer, and cell structure.